Common Medications

Most Common Antiepileptic Drugs


Trade Name
(Name used by the company to market the drug)

Generic Name
(Name based on the chemical composition of the drug)

Common Use
(Types of seizure the drug is most commonly used to control)

Possible Side Effects
(May require adjustment of drug dosage)

Serious Side Effects
(Usually requires discontinuation of the drug)

Carbatrol ®

Tegretol ®

Tegretol XR ®

carbamazepine

carbamazepine

carbamazepine, extended release

  • complex partial (psychomotor or temporal lobe)
  • generalized tonic-clinic (grand mal)
  • simple partial
  • drowsiness
  • dizziness
  • blurred vision
  • double vision
  • lethargy
  • nausea, vomiting
  • unsteadiness
  • allergic reaction
  • impaired liver function
  • bone marrow suppression
  • birth defects
  • Stevens-Johnson Syndrome (life threatening rash)
  • arrhythmia
  • seizures

Depakote ®

Depakene ®

divalproex sodium

valproic acid

  • absence (petit mal)
  • generalized tonic-clonic (grand mal)
  • complex partial
  • simple partial
  • nausea, vomiting
  • indigestion
  • sedation
  • dizziness, tremor
  • hair loss
  • liver function change
  • weight gain or loss
  • menstrual irregularities
  • fluid retention
  • allergic reaction
  • impaired liver function
  • bone marrow suppression
  • pancreatitis
  • Stevens-Johnson Syndrome
  • bleeding

Dilantin ®

phenytoin

  • generalized tonic-clonic
  • partial seizures
  • body hair increase
  • gum overgrowth
  • tremor
  • anemia
  • loss of coordination
  • double vision
  • nausea, vomiting
  • confusion
  • slurred speech
  • acne

 

  • allergic reaction
  • impaired liver function
  • SLE (Systemic Lupus Eryth.)
  • lymphoma
  • Purple Glove Syndrome
  • cardiovascular collapse
  • tissue necrosis
  • arrhythmia
  • bone marrow suppression

Diastat ®

diazepam

  • temporary add on therapy for controlling prolonged seizures
  • sleepiness
  • dizziness
  • headache

Felbatol ®

felbamate

  • generalized tonic-clinic
  • complex partial
  • secondary generalized (Lennox-Gastaut)
  • headache
  • insomnia
  • nausea
  • loss of appetite
  • allergic reaction
  • bone marrow suppression
  • liver failure

Gabitril ®

tigabine HCI

  • partial seizures
  • secondary generalized
  • dizziness
  • asthemia
  • somnolence
  • nausea
  • vomitingnervous
  • impaired momory
  • allergic reaction
  • central nervous system depression
  • seizures

Keppra ®

levetiracetam

  • add on therapy for partial seizures
  • drowsiness
  • behavioral/mood disorders
  • headache
  • loss of coordination
  • none reported

Klonopin ®

clonazepam

  • atonic
  • myoclonic
  • lethargy
  • dizziness
  • behavioral changes
  • increase in salivation
  • increase in bronchial secretions
  • clumsiness
  • hair loss
  • loss of appetite
  • allergic reaction
  • respiratory depression
  • impaired liver function
  • seizures

Lamictal ®

lamotrigine

  • partial seizures
  • generalized seizures
  • secondary generalized (Lennox-Gastaut)
  • nausea
  • dizziness
  • loss of coordination
  • rash
  • headache
  • allergic reaction
  • Stevens Johnson Syndrome
  • hepatic failure
  • bone marrow suppression

Mysoline ®

primidone

  • complex partial (psychomotor or temporal lobe)
  • generalized tonic-clonic (grand mal)
  • simple partial
  • drowsiness
  • loss of appetite
  • irritability
  • nausea, vomiting
  • dizziness
  • loss of coordination
  • allergic reaction
  • impaired liver function
  • dyspnea (shortness of breath)
  • lupus-like symptoms

Neurontin ®

gabapentin

  • add-on therapy for partial and generalized seizures
  • nausea
  • drowsiness
  • weight gain
  • dizziness
  • involuntary eye movement
  • leukopenia (low white blood cell count)

No Trade Name Commonly Used

phenobarbital

  • most types of seizures
  • irritability
  • dizziness
  • lethargy
  • hyperactivity
  • loss of coordination
  • loss of appetite
  • allergic reaction
  • Stevens-Johnson Syndrome
  • TTP (abnormality of blood cells)
  • respiratory depression
  • bone marrow suppression
  • angio edema

Topamax ®

topiramate

  • add-on therapy for partial seizures in adults
  • blurred vision
  • confusion, drowsiness
  • nausea, vomiting
  • kidney stones
  • dizziness
  • loss of coordination
  • glaucoma
  • allergic reaction
  • birth defects
  • nephrolithiasis

Tranxene ®

clorazepate

dipotassium

  • complex partial (psychomotor or temporal lobe)
  • drowsiness
  • dizziness
  • irritability
  • allergic reaction
  • impaired liver function

Trileptal ®

oxcarbazepine

  • complex partial (psychomotor or temporal lobe)
  • generalized tonic-clinic (grand mal)
  • simple partial
  • drowsiness
  • dizziness
  • blurred vision
  • double vision
  • lethargy
  • nausea, vomiting
  • unsteadiness
  • allergic reaction
  • impaired liver function
  • bone marrow suppression
  • hyponatraemia
  • birth defects
  • Stevens-Johnson Syndrome
  • angio edema

Zarontin ®

ethosuximide

  • absence (petit mal)
  • drowsiness
  • hyperactivity
  • nausea, vomiting
  • sleep disturbance
  • allergic reaction
  • impaired liver function
  • SLE (Systemic Lupus Eryth.)
  • Stevens-Johnson Syndrome
  • bone marrow suppression

Zonegran ®

zonisamide

  • add on therapy for partial, secondary generalized and tonic clonic seizures
  • anorexia
  • dizziness
  • fatigue
  • confusion
  • irritability
  • kidney stones
  • allergic reaction
  • Stevens-Johnson Syndrome
  • heat stroke
  • withdrawal seizures
  • bone marrow suppression
  • anaphylaxis

Educational Clicks


What is Epilepsy? Diagnostic Tests Treatment Options Common Medications Seizure First Aid


Mission
The Mission of the Epilepsy Center of Northwest Ohio is to improve the lives of people affected by epilepsy and those with developmental disabilities.

Vision
People with epilepsy and those with developmental disabilities will attain the highest quality of life and gain full acceptance and understanding from the community.



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